Artificial vision systems have been studied for years and one, called the Argus II, even reached the market and was installed in the eyes of about 400 people. But that product was later withdrawn after it proved to be a money-loser, according to Cortigent, the company that now owns that technology.
Thirty-eight patients in Europe received a PRIMA implant in one eye. On average, the study found, they were able to read five additional lines on a vision chart—the kind with rows of letters, each smaller than the last. Some of that improvement was due to what Sahel calls “various tricks” like using a zoom function, which allows patients to zero in on text they want to read.
The type of vision loss being treated with the new implant is called geographic atrophy, in which patients have peripheral vision but can’t make out objects directly in front of them, like words or faces. According to Prevent Blindness, an advocacy organization, this type of central vision loss affects around one in 10 people over 80.
The implant was originally designed starting 20 years ago by Daniel Palanker, a laser expert and now a professor at Stanford University, who says his breakthrough was realizing that light beams could supply both energy and information to a chip placed under the retina. Other implants, like Argus II, use a wire, which adds complexity.
“The chip has no brains at all. It just turns light into electrical current that flows into the tissue,” says Palanker. “Patients describe the color they see as yellowish blue or sun color.”
The system works using a wearable camera that records a scene and then blasts bright infrared light into the eye, using a wavelength humans can’t see. That light hits the chip, which is covered by “what are basically tiny solar panels,” says Palanker. “We just try to replace the photoreceptors with a photo-array.”
A diagram of how a visual scene could be represented by a retinal implant.
COURTESY SCIENCE CORPORATION
The current system produces about 400 spots of vision, which lets users make out the outlines of words and objects. Palanaker says a next-generation device will have five times as many “pixels” and should let people see more: “What we discovered in the trial is that even though you stimulate individual pixels, patients perceive it as continuous. The patient says ‘I see a line,’ “I see a letter.’”
